Other Chronic Diseases
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01
Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation
Masaaki Nakayama, et. al. (2017)
The data indicates E-HD could have substantial clinical benefits beyond conventional HD therapy, and support the rationale to conduct clinical trials of H2 application to HD treatment.
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02
Hydrogen Gas Alleviates Chronic Intermittent Hypoxia-Induced Renal Injury through Reducing Iron Overload
Peng Guan, et. al. (2019)
In conclusion, hydrogen may attenuate CIH-induced renal injury at least partially via inhibiting renal iron overload.
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03
Therapeutic effects of hydrogen on chronic graft‐versus‐host disease
Liren Qian, et. al. (2017)
The study suggests that hydrogen has a potential as an effective and safe therapeutic agent on cGVHD. This study will provide new ideas on the treatment of cGVHD and has important theoretical values.
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04
Promising novel therapy with hydrogen gas for emergency and critical care medicine
Motoaki Sano, et. al. (2018)
Studies undertaken by the Center have suggested possible therapeutic effects of hydrogen gas in relation to various aspects of emergency and critical care medicine, including acute myocardial infarction, cardiopulmonary arrest syndrome, contrast‐induced acute kidney injury, and hemorrhagic shock.
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05
Daily inhalation of hydrogen gas has a blood pressure‑lowering effect in a rat model of hypertension
Kazuhisa Sugai, et. al. (2020)
The conclusion suggests that 1-hour daily exposure to H2 exerts an anti-hypertensive effect in an animal model of hypertension.
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06
Beneficial effects of hydrogen gas inhalation on a murine model of allergic rhinitis
Shengjian Fang, et. al. (2018)
H2 inhalation induced a therapeutic effect on AR in a dose-dependent manner. The current results demonstrate that H2 may demonstrate a therapeutic value for allergic diseases.
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07
Molecular hydrogen: An inert gas turns clinically effective
Sergej M Ostojic. (2015)
Clinical profiles of H2 provide evidence-based direction for practical application and future research on molecular hydrogen for the wider health care community.
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08
Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine
Shigeo Ohta. (2014)
This study demonstrates that by regulating the gene expressions, H2 functions as an anti-inflammatory and anti-apoptotic, and stimulates energy metabolism. In addition to growing evidence obtained by model animal experiments, extensive clinical examinations were performed or are under investigation.
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09
Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals
J Slezák, et. al. (2016)
Application of molecular hydrogen in situations with excessive production of free radicals, in particular, hydroxyl and nitrosyl radicals is relatively simple and effective, therefore, it deserves special attention.
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10
Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis
Yayoi Murakami, MasafumiIto, and Ikuroh Ohsawa (2017)
In summary, H2 pretreatment prevented H2O2-induced cell death, enhanced mitochondrial activities, accompanied by an increased level of oxidative stress, and then induced expression of anti-oxidative enzymes.
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11
Hydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells
Junchao Yu, et. al. (2017)
The results demonstrated that H2 effectively reduced •OH, protected cells against oxygen toxicity resulting from HBO therapy, and had no effect on other ROS. Our data supported that H2 could be potentially used as an antioxidant during HBO therapy.
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12
Hydrogen gas inhalation inhibits progression to the "irreversible" stage of shock after severe hemorrhage in rats
Tadashi Matsuoka , et. al. (2017)
H2 gas inhalation delays the progression to irreversible shock. Clinically, H2 gas inhalation is expected to stabilize the subject until curative treatment can be performed, thereby increasing the probability of survival after hemorrhagic shock.
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